Dr. Qiuqiang ZHAN (詹求强)

 

Qiuqiang ZHAN, Ph.D., Associate Professor in Optics,

Graduate Supervisor,

Principle Investigator (PI),

Talent of Hong Kong Scholars program,

Talent of Pearl River S&T Nova Program of Guangzhou

 

詹求强，博士，副研究员，研究生导师，广东省杰出青年基金获得者、“香江学者计划”入选者、 “珠江科技新星”入选者

 

 

 

Summary (简介)

Area of working:

Optical imaging technology in modern microscopy (super-resolution imaging, multi-photon fluorescence imaging), nanophotonics and application of luminescent nanomaterials in biomedical theranotics.

研究领域：主要从事现代显微光学成像（超分辨显微成像、多光子荧光成像）、纳米光子学及光学纳米材料特性及应用等方面的研究。

Scientific achievements:

More than 30 peer-reviewed papers were published in international authoritative academic journals including Nature Communications, ACS Nano , Laser Photonics Review(2), Small, Theranotics, Biomaterials, Optics Express，Biomedical Optics Express, Nanotechnology. The number of citations for SCI articles is more than 950. First-authored paper published in ACS Nano is cited about 330 times. Many papers were rated as ESI Top papers, H-index: 13.

学术成果：近年来先后在Nature Communications, ACS Nano , Laser & Photonics Review(2), Small, Theranotics, Biomaterials, Nanoscale, Optics Express, Nanotechnology等国际权威学术期刊上发表文章三十多篇。SCI论文被引用总次数950次，其中第一作者ACS Nano文章被引用330次，多篇论文被评为“ESI全球前1%”优秀论文。

Other activities:

Invited as a reviewer for authoritative journals including ACS nano, Nano Today, Biomaterials, Nanoscale, Scientific Report, Optics Express, Biomedical Optics Express.

Invited as Local committee President of international conferences hosted abroad.

Instructing graduate student to apply for the CSC Scholarship and government-sponsored overseas study in European.

Instructing graduate student to attend international academic seminars and receive "Best Student Papers" Honors and Rewards.

Instructing undergraduate students to complement the national college students’ innovation project.

Instructing undergraduate to receive "Excellent Graduation Thesis" honor.

其他活动: 受邀担任ACS nano, Nano Today, Biomaterials, Nanoscale, Scientific Report, Optics Express, Biomedical Optics Express, PIER等权威期刊审稿人, 并曾受邀担任国外主办国际会议分会主席。指导研究生申请获批国家留学基金CSC奖学金并公派欧洲留学; 指导研究生参加国际学术研讨会议并获得“最佳学生论文”荣誉与奖励；指导本科生申请并获批国家级大学生创新项目；指导本科生毕业并获得全校“优秀毕业论文”。

Prizes and Awards:

The honor of ‘Hongkong Scholars’, Hongkong

Excellent college graduate of Zhejiang Province (Provincial level)

Excellent graduate of Zhejiang University

International exchange student scholarship of Lund University, Sweden

Communication scholarship of National Yang-Ming University

曾获奖励与荣誉包括：”香港学者” 荣誉，”珠江科技新星”荣誉, 浙江省高校优秀毕业生荣誉（省部级）、浙江大学优秀毕业研究生荣誉、瑞典隆德大学国际交流生奖学金和台湾阳明大学交流奖学金等。

Detailed Information (详细信息）

Study and Work Experience（学习和工作经历）

2012.7 – now Associate Professor in South China Normal University, Guangzhou, China

2012.7至今，于华南师范大学担任副研究员

2011 Visiting scholar in National Yang-Ming University, Taiwan, China

2011，以访问学者身份在台湾阳明大学访问交流

2009 - 2010 Visiting scholar in Lund University, Sweden

2009 – 2010，以访问学者身份在瑞典隆德大学访问交流

2007.9 - 2012.6 Doctor in optical engineering, Zhejiang University, China

2007.9 - 2012.6于浙江大学攻读光学工程专业博士学位。

2003.9 - 2007.6 Bachelor in Optical Information Science and Engineering, Shandong University, China

2003.9 - 2007.6 于山东大学攻读光信息科学与技术专业学士学位

Scientific Achievements（科研成果）

Refereed Journal Articles（发表论文）

Google Scholar: http://scholar.google.com/citations?user=Kduq6AEAAAAJ

or https://xue.glgoo.org/citations?user=Kduq6AEAAAAJ&hl=zh-CN&oi=ao  

ResearchGate: https://www.researchgate.net/profile/Qiuqiang_Zhan

 

·   Q. Zhan*(corresponding author), H. Liu, B. Wang, Q. Wu, R. Pu, C. Zhou, B. Huang, X. Peng, H. ?gren, S. He*, Achieving high-efficiency emission depletion nanoscopy by employing cross relaxation in upconversion nanoparticles. Nature Communications, 2017, 8, 1058.

·   Q. Zhan, J.Qian, H. Liang, S. He, et al “Using 915 nm laser excited Tm3+/Er3+/Ho3+ doped NaYbF₄ upconversion nanoparticles for in vitro and deeper in vivo bioimaging without overheating irradiation”, ACS Nano, 2011, 5, 3744-3757. (IF:13.94, JCR Q1, Times cited: 330)

·   Q. Zhan, X. Zhang, Y. Zhao, J. Liu, S. He. “Tens of thousands-fold upconversion luminescence enhancement induced by a single gold nanorod.” Laser & Photonics Reviews 2015, 9 (5), 479-487. (IF:8.43, JCR Q1)

·   C. T. Xu#, Q. Zhan# (equal contributor), Liu, H.; Somesfalean, G.; Qian, J.; He, S.; Andersson-Engels, S., “Upconverting nanoparticles for pre-clinical diffuse optical imaging, microscopy and sensing: Current trends and future challenges”, Laser & Photonics Reviews 2013, 1-35. (IF:8.43, JCR Q1)

·   Q. Zhan, S. L. He, J. Qian, H. Cheng, F. H. Cai “Optimization of Optical Excitation of Upconversion Nanoparticles for Rapid Microscopy and Deeper Tissue Imaging with Higher Quantum Yield”, Theranostics, 2013, 3 (5), 306-316.(IF:8.76, JCR Q1)

·   R. Wu, Q. Zhan*(corresponding author), H. Liu, X. Wen, B. Wang, S. He. “Optical depletion mechanism of upconverting luminescence and its potential for multi-photon STED-like microscopy.” Optics Express 2015,23 (25), 32401-32412 (JCR Q2)

·  B. Wang, Q. Zhan*(corresponding author), Y. Zhao, R. Wu, J. Liu, S. He. “Visible-to-visible four-photon ultrahigh resolution microscopic imaging with 730-nm diode laser excited nanocrystals.” Optics Express 2016, 24 (2), A302-A311 (JCR Q2)

·  Wu Q, Huang B, Peng X, He S, Q. Zhan*(corresponding author). Non-bleaching fluorescence emission difference microscopy using single 808-nm laser excited red upconversion emission. Optics Express, 2017, 25, 30885-30894.

·   Y. Zhao, Q. Zhan*(corresponding author); J. Liu, S. He,“Optically investigating Nd 3+-Yb 3+ cascade sensitized upconversion nanoparticles for high resolution, rapid scanning, deep and damage-free bio-imaging.” Biomedical optics express 2015, 6 (3), 838-848.  (JCR Q2)

·   Q. Zhan, Baoju Wang, Xuanyuan Wen and Sailing He*, "Controlling the excitation of upconverting luminescence for biomedical theranostics: neodymium sensitizing." Optical Materials Express, 2016, 6(4): 1011-1023.

·   Q Ding, Q Zhan, X Zhou, T Zhang, D Xing - Theranostic Upconversion Nanobeacons for Tumor mRNA Ratiometric Fluorescence Detection and Imaging‐Monitored Drug Delivery, Small, 2016 (JCR Q1)

·   Liu, H.; Huang, K.; Valiev, R. R.; Zhan, Q.; Zhang, Y.; ?gren, H., Photon Upconversion Kinetic Nanosystems and Their Optical Response. Laser & Photonics Reviews 2018, 12. (IF:8.43, JCR Q1)

·   J. Liu, R. Wu, N. Li, X. Zhang, Q. Zhan*(corresponding author); S. He, “Deep, high contrast microscopic cell imaging using three-photon luminescence of B-(NaYF₄:Er³⁺/NaYF₄) nanoprobe excited by 1480-nm CW laser of only 1.5-mW.”Biomedical Optics Express 2015, 6 (5), 1857-1866. (JCR Q2)

·   Nana Li, Xuanyuan Wen, Jing Liu, Baoju Wang, Q. Zhan*(corresponding author) and Sailing He, "Yb3+-enhanced UCNP@SiO2 nanocomposites for consecutive imaging, photothermal-controlled drug delivery and cancer therapy" Optical Materials Express , 2016 ,6(4): 1161-1171.

·   J. Liu, N. Li, R. Wu, Y. Zhao, Q. Zhan*(corresponding author), S. He, "Sub-5-nm lanthanide-doped ZrO 2@ NaYF₄ nanodots as efficient upconverting probes for rapid scanning microscopy and aptamer-mediated bioimaging."Optical Materials Express 2015,5 (8), 1759-1771 (JCR Q2)

·  X. Wen, B. Wang, R. Wu, N. Li, S. He, Q. Zhan* (corresponding author). “Designed Er³⁺-singly doped NaYF₄ with double excitation bands for simultaneous deep macroscopic and microscopic upconverting bioimaging.” Optics Express, 2016, 7(6):2174.  (JCR Q2)

· Tan, C.; Su, X.; Zhou, C.; Wang, B.; Q. Zhan*(corresponding author); He, S., Acid-assisted hydrothermal synthesis of red fluorescent carbon dots for sensitive detection of[space]Fe(iii). RSC Advances 2017, 7, 40952-40956.  (IF: 3.01)

·   Li, Z.; Gao, L.; Wang, S.; Ji, S.; Tan, J.; Peng, X.; Zhan, Q.*; Huo, Y., Two cubane-type Ln4(OH)4 compounds derived from tridentate ligand 8-hydroxyquinoline: Synthesis, structures, one/two-photon luminescence and magnetism. Journal of Luminescence 2018, 198, 208-214.  (IF: 2.65) 

·   Q. Zhan, J. Qian, X. Li and S. He "A Study of Mesoporous Silica-encapsulated Gold Nanorods as Enhanced Light Scattering Probes for Cancer Cell Imaging" Nanotechnology, 21(2010), 055704.

·   J. Qian; D. Wang; F. Cai; Q. Zhan; Y. Wang; S. He, Photosensitizer Encapsulated Organically Modified Silica Nanoparticles for Direct Two-photon Photodynamic Therapy and In Vivo Functional Imaging. Biomaterials 2012, 33 (19), 4851-4860. (JCR Q1)

·   J. Qian, T. Fu, Q. Zhan and S. He (invited review paper), “Using Some Nanoparticles as Contrast Agents for Optical Bio-imaging”, IEEE Journal of Selected Topics in Quantum Electronics, 2010, 16 (3), 672-684.

·   Y. Cui, H. Zhao, F. Yang, P. Tong, Y. Hao, Q. Sun, F. Shi, Q. Zhan, H. Wang, F. Zhu. “Efficiency enhancement in organic solar cells by incorporating silica-coated gold nanorods at the buffer/active interface.” Journal of Materials Chemistry C 2015,3 (38), 9859-9868

·  Sathishkumar, P.; Gu, F. L.; Zhan, Q.; Palvannan, T.; Mohd Yusoff, A. R., Flavonoids mediated ‘Green’ nanomaterials: A novel nanomedicine system to treat various diseases – Current trends and future perspective. Materials Letters 2018, 210, 26-30.

·  Zhang, D.-Y.; Zheng, Y.; Zhang, H.; He, L.; Tan, C.-P.; Sun, J.-H.; Zhang, W.; Peng, X.; Zhan, Q.; Ji, L.-N.; Mao, Z.-W., Ruthenium complex-modified carbon nanodots for lysosome-targeted one- and two-photon imaging and photodynamic therapy. Nanoscale 2017, 9, 18966-18976.

·   X. Li, L. Jiang, Q. Zhan, J. Qian and S. He, “Localized Surface Plasmon Resonance (LSPR) of Polyelectrolyte-functionalized Gold-nanoparticles for Bio-sensing”, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2009, 332,172-179.

·   X. Liu, J. Lin, T. Jiang, Z. Zhu, Q. Zhan, J. Qian, and S. He, "Surface plasmon properties of hollow Au-Ag alloyed triangular nanoboxes and its applications in sers imaging and potential drug delivery," Progress In Electromagnetics Research, Vol. 128, 35-53, 2012

·   J. Qian, Y. Wang, X. Gao, Q. Zhan, Z. Xu and S. He, “Carboxyl-functionalized and Bio-conjugated Silica coated Quantum Dots as Targeting Probes for Cell Imaging,” Journal of Nanoscience and Nanotechnology, 2010, 10(1-8).

·  Y. Wei, L. Quan, C. Zhou, and Q. Zhan*, “Factors relating to the biodistribution & clearance of nanoparticles & their effects on in vivo application”, Nanomedicine, 2018 13:12, 1495-1512

Patents（专利） 

1. 詹求强，吴锐涛，王保举，一种荧光损耗方法、显微成像方法及显微成像装置，中国发明专利，专利号：ZL 201510896605.8，授权（公告）日：2018.06.19

2. 詹求强，赵宇翔，王保举，钕离子敏化上转换纳米晶新用途及高分辨多光子显微系统，中国发明专利，专利号：ZL 201510400885.9，授权（公告）日：2018.02.16

3. 詹求强，刘静，上转换复合纳米材料及其制备方法、应用，中国发明专利，专利号：ZL 201410331538.0，授权(公告)日：2017.04.05 

4. 詹求强，丁诗雨，蒲锐，一种近红外光激发上转换长余辉的复合纳米材料及其制备，中国发明专利，专利号：ZL 201610279154.8，授权(公告)日：2018.05.01

5. 詹求强，刘静，赵宇翔，一种单光束生物细胞检测及筛选的微流控系统及方法，中国发明专利，专利号：ZL 201310404958.0,  授权(公告)日：2016-05-11

6. 詹求强，赵宇翔，一种简便的超宽带受激拉曼光谱显微成像系统，中国发明专利，专利号：ZL 201310422918.0, 授权(公告)日：2015.06.10

7. 王丹，钱骏，詹求强，何赛灵，一种新型的上转换发光材料的牛血清包覆方法，中国发明专利，专利号：ZL 201210060849.9, 授权(公告)日：2014.01.29

8. 王丹，钱骏，詹求强，何赛灵，一种上转换荧光纳米材料的制备方法，中国发明专利，专利号：ZL 201110006719.2, 授权(公告)日：2013.03.13

9. 詹求强，王保举，蒲锐，彭星韵，黄冰如，一种受激辐射损耗方法、超分辨成像方法及显微成像装置，中国发明专利，公开号：CN105572084A，公开日：2017.05.11

10. 詹求强，周超，黄冰如，上转换超分辨成像纳米探针及其制备方法和应用，中国发明专利，公开号：CN107629792A，公开日2018.01.26

11. 詹求强，何赛灵，杨东尼，林众宇，潘江帆，基于上转换纳米晶的受激损耗超分辨光学显微方法及系统，中国发明专利，公开号：104764729A，公开日：2015.07.08

12. 詹求强，吴秋生，马剑涛，王保举，李彦慧，基于DMD的双模式光学超分辨显微成像装置及方法，中国发明专利，公开号：CN107167929A，公开日2017.09.15

13. 詹求强，彭星韵，吴秋生，黄冰如，蒲锐，一种多波段荧光损耗方法、多色超分辨成像方法及装置，中国发明专利，申请号：201710919396.3，申请日：2017年9月30日

14. 詹求强，叶峰，吴秋生，黄雯文，姚丽琴，黄冰如，基于上转换纳米材料的多焦点结构光照明显微成像装置，中国发明专利，申请号：201820304942.2

15. 詹求强，吴秋生，黄冰如，周超，黄文雯，一种荧光成像方法、实时差分超分辨显微成像方法及装置，中国发明专利，申请号：201810418783.3，申请日：2018年5月4日

Grants & Projects（项目） 

·广东省杰出青年基金项目，主持人，2018.01-2021.12

·国家自然科学基金面上项目，主持人，2017.01-2020.12

·国家自然科学基金青年项目，主持人，2015.01-2017.12

·广州市“珠江科技新星”创新人才项目，主持人，2017.01-2019.12

·广东省自然科学基金（面上项目），主持人，2015.01-2017.01;

·中国博士后科学基金面上（一等），主持人，2016.10-2017.12

·中国博士后科学基金面上（特别资助），主持人，2014. 07-2015.12;

·光电子器件与系统教育部重点实验室开放课题基金（深圳大学），主持人，2017.01-2018.12；

·广东省自然科学基金博士启动项目，主持人，2013.10-2015.10;·中国博士后科学基金面上（一等），主持人，2013.06-2015.12;

·广东省学科建设经费（优秀青年计划项目），主持人，2013.10-2015.12;

·华南师范大学青年教师培养基金，主持人，2012.12-2014.12;

作为骨干人员，参与研究国家863重大项目、国家基金重点项目、国家基金面上项目等。

 

Contact Information （联系信息）

E-mail: zhanqiuqiang@m.scnu.edu.cn 

Tel: 020-34725816 # 8305；Fax: 020-34728410

Rm 305, Science Bldg No. 5, South China Normal University, Universiity City, Panyu District, Guangzhou 510006, China

广州市番禺区广州大学城华南师范大学理5栋305室，邮编510006